Sensitivity analysis in a camera-LiDAR calibration model

Recientemente, la fusión de datos entre una cámara y un sensor de profundidad del tipo LiDAR se ha convertido en un problema de gran interés en la industria y en la ingeniería. La calidad de los modelos 3D producidos depende, en buena manera, de un proceso correcto de calibración entre ambos sensores. En este artículo, se realiza un análisis de sensibilidad en un modelo de calibración cámara-LiDAR. Se ha calculado individualmente la variabilidad de cada parámetro por el método de Sobol, basado en la técnica de ANOVA, y el método FAST, que se basa en el análisis de Fourier. Se han definido los parámetros más sensibles y con mayor tendencia a introducir errores en nuestra plataforma de reconstrucción. Se han simulado múltiples conjuntos de parámetros para su análisis y comparación utilizando los métodos de Monte Carlo e Hipercubo Latino. Se muestran estadísticas sobre la sensibilidad total y global de cada parámetro. Además, se presentan resultados sobre la relación de sensibilidad en la calibración cámara-LiDAR, el costo computacional, el tiempo de simulación, la discrepancia y la homogeneidad en los datos simulados.Recently the data fusion between a camera and a depth sensor of LiDAR type, has become an issue of major concern in industry and engineering. The quality of the delivered 3D models depends greatly on a proper calibration between sensors. This paper presents a sensitivity analysis in a camera-lidar calibration model. The variability of each parameter was calculated individually by the Sobol method, based on ANOVA technique, and the FAST method, which is based on Fourier analysis. Multiple sets of parameters were simulated using Monte Carlo and Latin Hypercube methods for the purpose of comparing the results of the sensitivity analysis. We defined which parameters are the most sensitive and prone to introduce error into our reconstruction platform. Statistics for the total and global sensibility analysis for each sensor and for each parameter are presented. Furthermore, results on the sensitivity ratio on camera-LiDAR calibration, computational cost, time simulation, discrepancy and homogeneity in the simulated data are presented.Peer Reviewe

Actitud hacia las personas mayores y variables asociadas en un grupo de estudiantes universitarios del ámbito de la educación

Attitudes are defined as a construct that implies a state of mental disposition (cognitive and affective aspects) that influence our perception, thinking and motivation, and direct our behaviors. Attitudes become determinant elements in predicting positive or negative behaviors towards others, especially towards the elderly. The aim of this study is to know the attitudes of the students of university degrees in education, since they will be the next professionals to educate. Knowing the attitudes and variables that may influence them may be a key aspect for developing subsequent interventions, as well as for improving attitudes towards the elderly and, therefore, their care. This study shows that the attitude is moderately positive, and that a more positive attitude is related to having interest in old age issues, and to four human strengths such as love, kindness, gratitude and humility. Las actitudes se definen como un constructo que implica un estado de disposición mental (aspectos cognitivos y afectivos) que influyen en nuestra percepción, pensamiento y motivación, y dirigen nuestras conductas. Las actitudes se convierten en elementos determinantes para predecir conductas positivas o negativas hacia los demás, especialmente hacia las personas mayores. El objetivo de este estudio es conocer las actitudes del alumnado de títulos universitarios de educación, ya que serán los próximos profesionales que eduquen. Conocer las actitudes y variables que puedan influir en estas puede ser un aspecto clave para desarrollar intervenciones posteriores, así como, para mejorar las actitudes hacia el mayor, y, por ende, su atención. Este estudio muestra que la actitud es moderadamente positiva, y que una actitud más positiva está relacionada con tener interés por temas de vejez, y con cuatro fortalezas humanas como son el amor, la bondad, la gratitud y la humildad

Does the addition of manual therapy approach to a cervical exercise program improve clinical outcomes for patients with chronic neck pain in short-and mid-term? A randomized controlled trial

Chronic neck pain is one of today’s most prevalent pathologies. The International Classification of Diseases categorizes four subgroups based on patients’ associated symptoms. However, this classification does not encompass upper cervical spine dysfunction. The aim is to compare the short-and mid-term effectiveness of adding a manual therapy approach to a cervical exercise protocol in patients with chronic neck pain and upper cervical spine dysfunction. Fifty-eight subjects with chronic neck pain and upper cervical spine dysfunction were recruited (29 = Manual therapy + Exercise; 29 = Exercise). Each group received four 20-min sessions, one per week during four consecutive weeks, and a home exercise regime. Upper flexion and flexion-rotation test range of motion, neck disability index, craniocervical flexion test, visual analogue scale, pressure pain threshold, global rating of change scale, and adherence to self-treatment were assessed at the beginning, end of the intervention and at 3-and 6-month follow-ups. The Manual therapy + Exercise group statistically improved short-and medium-term in all variables compared to the Exercise group. Four 20-min sessions of Manual therapy + Exercise along with a home-exercise program is more effective in the short-to mid-term than an exercise protocol and a home-exercise program for patients with chronic neck pain and upper cervical dysfunction

Patrones y estrategias de regulación emocional empleadas en personas mayores de 60 años con deterioro cognitivo.

Introducción. Son escasos los estudios científicos sobre los patrones cognitivos y estrategias empleadas en personas mayores con deterioro cognitivo (DC). Objetivo. El objetivo fue comparar 2 grupos de personas mayores, con DC y sin DC, la refocalización de planes, catastrofización, autoculpa, refoca-lización positiva y reinterpretación positiva para observar diferencias y establecer patrones cognitivos adaptados al perfil para la mejora en la atención profesional. Método. Para ello en este estudio de corte transversal con diseño correlacional y muestreo no probabilístico por conveniencia se empleó el Cog-nitive Emotion Regulation Questionnaire (CERQ) y Geriatric Depression Scale (GDS) en 196 personas mayores de 60 años pertenecientes a centros de día y residencias (M= 75,95 DT= 10,08). Resultados. Se han obtenido resultados estadísticamente significativos en refocalización de planes (p <. 00); catas-trofización (p= .00); autoculpa (p <. 00); refocalización positiva (p <. 00) reinterpretación positiva (p <. 00). Conclusiones. Es uno de los escasos estudios de este campo que contribuye a enfatizar la necesidad de estudio de variables emocionales adaptativas o desadaptativas para la vida del adulto mayor con DC inexistentes en el ámbito científico, además, muestra diferentes patrones cognitivos y estrategias adaptativas empleadas en DC y sin DC. Su conocimiento ayudaría a personalizar intervenciones en función de los patrones cognitivos presentes en esta publicaciónScientific studies on cognitive patterns and strategies used in older people with cognitive impair-ment (CD) are scarce. Objective: The objective was to compare 2 groups of older people, with CD and without CD, the refocusing of plans, catastrophizing, self-blame, positive refocusing and positive rein-terpretation to observe differences and establish cognitive patterns adapted to the profile for the impro-vement in professional care. Method: For this, in this cross-sectional study with correlational design and probability sampling by not convenience, the Cognitive Emotion Regulation Questionnaire (CERQ) and Geriatric Depression Scale (GDS) were used in 196 people over 60 years old belonging to day centers and residences (M=75.95 SD= 10.08) Results: Statistically significant results have been obtained in re-focusing plans (p<.00); catastrophizing (p=.00); self-blame (p<.00); positive refocusing (p<.00); positive reinterpretation (p<.00). Conclusions: It is one of the few studies in this field that contributes to empha-size the need to study adaptative or maladaptative emotional variables for the life of the elderly with CD that do not exist in the scientific field, in addition, it shows different cognitive patterns and adaptative strategies used in CD and without DC. Their knowledge would help to personalize interventions based on the cognitive patterns present in this publicatio

Widespread Environmental Presence of Multidrug-Resistant Salmonella in an Equine Veterinary Hospital That Received Local and International Horses

Indexación: Scopus.Salmonella enterica is a highly infectious microorganism responsible for many outbreaks reported in equine hospitals. Outbreaks are characterized by high morbidity and mortality rates, nosocomial transmission to other patients, zoonotic transmission to hospital personnel, and even closure of facilities. In this study, 545 samples (environmental and hospitalized patients) were collected monthly during a 1-year period from human and animal contact surfaces in an equine hospital that received local and international horses. A total of 22 Salmonella isolates were obtained from human contact surfaces (e.g., offices and pharmacy) and animal contact surfaces (e.g., stalls, surgery room, and waterers), and one isolate from a horse. Molecular serotyping revealed 18 isolates as Salmonella Typhimurium and three as Salmonella Infantis. Nineteen isolates were resistant to at least one antimicrobial class, and only two isolates were susceptible to all antimicrobials tested. In addition, we identified nine multidrug-resistant (MDR) isolates in S. Typhimurium, which displayed resistance to up to eight antimicrobials (i.e., amoxicillin/clavulanate, ampicillin, ciprofloxacin, chloramphenicol, streptomycin, gentamicin, trimethoprim/sulfamethoxazole, and tetracycline). Pulsed-field gel electrophoresis (PFGE) revealed the presence of three PFGE patterns permanently present in the environment of the hospital during our study. The persistent environmental presence of MDR Salmonella isolates, along with the fact that local and international horses are attended in this hospital, highlights the importance of improving biosecurity programs to prevent disease in horses and the hospital personnel and also for the global dissemination and acquisition of MDR Salmonella. © Copyright © 2020 Soza-Ossandón, Rivera, Tardone, Riquelme-Neira, García, Hamilton-West, Adell, González-Rocha and Moreno-Switt.https://www.frontiersin.org/articles/10.3389/fvets.2020.00346/ful

Pathological response in a triple-negative breast cancer cohort treated with neoadjuvant carboplatin and docetaxel according to Lehmann's refined classification

Purpose: Triple-negative breast cancer (TNBC) requires the identification of reliable predictors of response to neoadjuvant chemotherapy (NACT). For this purpose, we aimed to evaluate the performance of the TNBCtype-4 classifier in a cohort of patients with TNBC treated with neoadjuvant carboplatin and docetaxel (TCb). Methods: Patients with TNBC were accrued in a nonrandomized trial of neoadjuvant carboplatin AUC 6 and docetaxel 75 mg/m2 for six cycles. Response was evaluated in terms of pathologic complete response (pCR, ypT0/is ypN0) and residual cancer burden by Symmans and colleagues. Lehmann's subtyping was performed using the TNBCtype online tool from RNAseq data, and germline sequencing of a panel of seven DNA damage repair genes was conducted. Results: Ninety-four out of the 121 patients enrolled in the trial had RNAseq available. The overall pCR rate was 44.7%. Lehmann subtype distribution was 34.0% BL1, 20.2% BL2, 23.4% M, 14.9% LAR, and 7.4% were classified as ERþ. Response to NACT with TCb was significantly associated with Lehmann subtype (P ¼ 0.027), even in multivariate analysis including tumor size and nodal involvement, with BL1 patients achieving the highest pCR rate (65.6%), followed by BL2 (47.4%), M (36.4%), and LAR (21.4%). BL1 was associated with a significant younger age at diagnosis and higher ki67 values. Among our 10 germline mutation carriers, 30% were BL1, 40% were BL2, and 30% were M. Conclusions: TNBCtype-4 is associated with significantly different pCR rates for the different subtypes, with BL1 and LAR displaying the best and worse responses to NACT, respectively

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results

Jet size dependence of single jet suppression in lead-lead collisions at sqrt(s(NN)) = 2.76 TeV with the ATLAS detector at the LHC

Measurements of inclusive jet suppression in heavy ion collisions at the LHC provide direct sensitivity to the physics of jet quenching. In a sample of lead-lead collisions at sqrt(s) = 2.76 TeV corresponding to an integrated luminosity of approximately 7 inverse microbarns, ATLAS has measured jets with a calorimeter over the pseudorapidity interval |eta| < 2.1 and over the transverse momentum range 38 < pT < 210 GeV. Jets were reconstructed using the anti-kt algorithm with values for the distance parameter that determines the nominal jet radius of R = 0.2, 0.3, 0.4 and 0.5. The centrality dependence of the jet yield is characterized by the jet "central-to-peripheral ratio," Rcp. Jet production is found to be suppressed by approximately a factor of two in the 10% most central collisions relative to peripheral collisions. Rcp varies smoothly with centrality as characterized by the number of participating nucleons. The observed suppression is only weakly dependent on jet radius and transverse momentum. These results provide the first direct measurement of inclusive jet suppression in heavy ion collisions and complement previous measurements of dijet transverse energy imbalance at the LHC.Comment: 15 pages plus author list (30 pages total), 8 figures, 2 tables, submitted to Physics Letters B. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2011-02

Epidemiological trends of HIV/HCV coinfection in Spain, 2015-2019

Altres ajuts: Spanish AIDS Research Network; European Funding for Regional Development (FEDER).Objectives: We assessed the prevalence of anti-hepatitis C virus (HCV) antibodies and active HCV infection (HCV-RNA-positive) in people living with HIV (PLWH) in Spain in 2019 and compared the results with those of four similar studies performed during 2015-2018. Methods: The study was performed in 41 centres. Sample size was estimated for an accuracy of 1%. Patients were selected by random sampling with proportional allocation. Results: The reference population comprised 41 973 PLWH, and the sample size was 1325. HCV serostatus was known in 1316 PLWH (99.3%), of whom 376 (28.6%) were HCV antibody (Ab)-positive (78.7% were prior injection drug users); 29 were HCV-RNA-positive (2.2%). Of the 29 HCV-RNA-positive PLWH, infection was chronic in 24, it was acute/recent in one, and it was of unknown duration in four. Cirrhosis was present in 71 (5.4%) PLWH overall, three (10.3%) HCV-RNA-positive patients and 68 (23.4%) of those who cleared HCV after anti-HCV therapy (p = 0.04). The prevalence of anti-HCV antibodies decreased steadily from 37.7% in 2015 to 28.6% in 2019 (p < 0.001); the prevalence of active HCV infection decreased from 22.1% in 2015 to 2.2% in 2019 (p < 0.001). Uptake of anti-HCV treatment increased from 53.9% in 2015 to 95.0% in 2019 (p < 0.001). Conclusions: In Spain, the prevalence of active HCV infection among PLWH at the end of 2019 was 2.2%, i.e. 90.0% lower than in 2015. Increased exposure to DAAs was probably the main reason for this sharp reduction. Despite the high coverage of treatment with direct-acting antiviral agents, HCV-related cirrhosis remains significant in this population